Desoxo-narchinol A
CAS No. 53859-06-6
Desoxo-narchinol A ( —— )
产品货号. M31583 CAS No. 53859-06-6
Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytotoxic activity against P-388 cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥7503 | 有现货 |
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50MG | 获取报价 | 有现货 |
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100MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称Desoxo-narchinol A
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytotoxic activity against P-388 cells.
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产品描述Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytotoxic activity against P-388 cells.
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体外实验Desoxo-narchinol A inhibits tissue injury and production of pro-inflammatory cytokines, such as IL-1β, IL-6, and TNF-α, in the liver and lung.Desoxo-narchinol A (0-500 nM, 24 h) inhibits the production of inflammatory mediators, such as iNOS and its derivative NO, COX-2, PGE2, IL-1β, IL-6 and TNF-α and H3 protein acetylation in murine peritoneal macrophages.Desoxo-narchinol A inhibits LPS-induced activation of p38 in murine macrophages.
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体内实验Desoxo-narchinol A (0-0.5 mg/kg, IP, once) dramatically reduced mortality in a murine LPS-induced endotoxin shock model. Desoxo-narchinol A (50 mg/kg, PO, once) shows the oral bioavailability of 18.1% in rats and 28.4% in mice
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number53859-06-6
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分子量192.25
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分子式C12H16O2
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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